Sep 1, 2012 · Type III myeloblast: more than 15 - 20 cytoplasmic granules but otherwise has features of a blast cell Promyelocyte: 10 - 20 microns; increased basophilic cytoplasm (compared to blasts) with primary coarse red purple, azurophilic granules; large, round / oval nucleus with red blue and fine to slightly condensed chromatin; 1 - 2 nucleoli; N/C ...

Nov 21, 2022 · CD34 and CD117 typically present on the myeloblast population, which may be small Monocytic cells typically express CD14, CD64, CD11b, CD11c, CD4, CD36, CD68 (PGM1), CD163, lysozyme; Most cases express HLA-DR; Coexpression of CD15, CD36 and CD64 is characteristic of monocytic differentiation Reference: Am J Clin Pathol 2004;122:865

Dec 9, 2021 · Comment: Flow cytometry immunophenotyping performed on bone marrow aspirate shows an aberrant myeloblast population (0.8% of total events) with the following immunophenotype: CD7 partial, CD13+, CD33+, CD34+, CD117 inc and CD38 dec. Hematogones are absent. No monoclonal B cells or immunophenotypically abnormal T cells …

Feb 15, 2021 · Bone marrow neoplastic Bone marrow - plasma cell and lymphoid neoplasms Other Acute lymphoblastic leukemia / lymphoma

Aug 1, 2012 · Eosinophilic promyelocyte: intermediate in development between a myeloblast and myelocyte; 15 microns in diameter with large nucleus and nucleolus; contains a few undifferentiated (primary, coreless) cytoplasmic granules in intensely basophilic cytoplasm

Jan 25, 2024 · Myeloperoxidase (MPO) is a myeloid marker that stains neutrophils strongly and other granulocytes variably.

Apr 3, 2025 · Primary myelofibrosis is an uncommon myeloproliferative neoplasm characterized by a proliferation of predominantly abnormal megakaryocytes and granulocytes in the ...

Feb 1, 2013 · Leukemia - Acute - Acute monoblastic leukemia (M5a)

May 20, 2021 · Most patients are asymptomatic but may present with myeloblast organ infiltration: Hepatosplenomegaly (common) Ascites, pericardial or pleural effusions, hepatic fibrosis, disseminated intravascular coagulopathy (less common) Severe organ dysfunction causing renal, hepatic or cardiopulmonary failure (rare)

Feb 1, 2013 · Criteria for diagnosis: 90%+ of nonerythroid cells in marrow are myeloblasts; 10% granulocytic elements; 3%+ of blasts must be positive for myeloperoxidase or Sudan Black B and / or Auer rods by enzyme cytochemistry