The presence of mucin pools lacking neoplastic epithelium ("acellular" mucin) in resection specimens of rectal carcinoma after neoadjuvant chemoradiotherapy (CRT) is a well …

Jan 6, 2015 · Acellular mucin pools in the rectal wall and lymph nodes after neoadjuvant treatment (H&E stains). The depth of invasion and margin should be diagnosed based on the …

Epithelia are protected from adverse conditions by a mucous barrier. The secreted and transmembrane mucins that constitute the mucous barrier are largely unrecognized as …

Jan 20, 2015 · Results: Mucin pools were present in 182 specimens (40.8%); 66 (14.7%) were acellular, and viable tumor cells were identified in 116 (26.0%). If acellular mucin is considered …

The presence of mucin pools following neoadjuvant chemoradiotherapy for rectal cancer represents a surrogate marker of response to treatment and downstaging and is associated …

Feb 4, 2020 · Mucin pools are a gel-like substance found extracellularly in some patients with rectal cancer following treatment with chemoradiotherapy.

Mar 21, 2017 · Evaluation and response of mucin pools in primary rectal cancer tissue during chemoradiotherapy (CRT). Retrospective review of outcomes in patients (pts) with …

Feb 3, 2023 · Our results showed that patients with acellular mucin pools have a higher rate of distant metastases and that acellular mucin pools were risk factors for 5-year DFS and 5-year …

Jun 14, 2014 · Serosal involvement in colorectal cancer is staged as T4, which is associated with decreased survival and may impact additional therapy decisions. Although careful sampling …

Neoadjuvant chemoradiotherapy (CRT) is the standard of care for locally advanced rectal cancer. Morphologic changes such as fibrosis, inflammatory infiltrates, and the formation of …