May 2, 2022 · What is mucinous carcinoma? Mucinous carcinoma is a rare type of cancer. In mucinous carcinoma, cancer cells form in mucin, the main component of mucus. Mucins are …

Mucin 1 (MUC1) was the first discovered transmembrane protein of the mucin family; it normally covers epithelial cells of the mucous membrane, providing lubrication and protection. …

Metastatic urothelial cancer (mUC) is a molecularly heterogeneous disease with diverse potential drivers of progression and mechanisms of therapeutic response and resistance. 1 For over 3 …

Sep 18, 2018 · What is mucinous carcinoma? Mucinous carcinoma is an invasive type of cancer that begins in an internal organ that produces mucin, the primary ingredient of mucus. The …

Tumor-associated mucins (MUC) promote an immunosuppressive microenvironment by either masking Toll-like receptors (TLRs) on antigen-presenting cells (APCs) or inhibiting synapse …

In cancer cells, MUC1 participates in intracellular signal transduction pathways and regulates the expression of its target genes at both the transcriptional and post-transcriptional levels. This …

This Review highlights the functions of mucins in cancer and discusses how these proteins are being targeted therapeutically. Epithelia are protected from adverse conditions by a mucous …

Background: Mucin (MUC) is a family of high-molecular weight glycoproteins and increased mucin production occurs in many malignant tumors. Recent studies have found relationship between …

Oct 17, 2021 · With their unique biological and structural features, MUC proteins have been considered promising therapeutic targets and also biomarkers for human cancer. In this …

Mucins (MUC) protect epithelial barriers from environmental insult to maintain homeostasis. However, their aberrant overexpression and glycosylation in various malignancies facilitate …