Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such …

Mar 30, 2025 · MMP15 (Matrix Metallopeptidase 15) is a Protein Coding gene. Diseases associated with MMP15 include Glottis Squamous Cell Carcinoma and Supraglottis Cancer. Among its related pathways are Matrix metalloproteinases and Extracellular matrix organization.

Jan 4, 2025 · Gene target information for MMP15 - matrix metallopeptidase 15 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC).

Jul 2, 2020 · Here, we describe MMP15 placental location in early human pregnancy and assess whether MMP15 plays a pivotal role in CTB invasion. We also hypothesize that maternal obesity affects MMP15 regulation.

Assigned HPA protein class (es) for the encoded protein (s). Number of protein-coding transcripts from the gene as defined by Ensembl. A summary of the overall protein expression profile across the analyzed normal tissues based on knowledge-based annotation, presented in the Tissue resource. "Estimation of protein expression could not be performed.

Matrix metalloproteinases (MMPs), such as MMP15, are zinc-binding endopeptidases that degrade various components of the extracellular matrix. They have been implicated in normal and pathologic processes including tissue remodeling, wound …

Mar 28, 2023 · Expression of MMP15 was immunohistochemically detected in a tissue microarray of formalin-fixed paraffin-embedded samples from 95 patients of PDAC after surgery. Its expression pattern and relations with clinicopathologic factors and disease-specific survival (DSS) were then evaluated.

Here, we characterize the impact of global Mmp14 and Mmp15 targeting on early postnatal mammary gland development in mice. Unexpectedly, both Mmp14−/− and Mmp15−/− mammary glands retain the ability to generate intact ductal networks.

Nov 15, 2011 · Mice with targeted snai1 knockdown display hypocellular ECs at E10.5 associated with decreased expression of mesenchyme cell markers and downregulation of the matrix metalloproteinase (mmp) family member, mmp15.