Minimum alveolar concentration or MAC is the concentration, often expressed as a percentage by volume, of a vapour in the alveoli of the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) stimulus.

Sep 10, 2024 · Minimum alveolar concentration (MAC) provides a correlation between anesthetic dose and immobility. It can be applied to all inhalational anesthetics and is used to compare anesthetic potency.

MAC is defined as the minimum alveolar concentration of inhaled anesthetic at sea level required to suppress movement to a surgical incision in 50% of the patients. It is often referred to as the ED 50 for immobility, MAC-movement, or median alveolar concentration.

Feb 16, 2013 · Since its introduction in 1965, minimum alveolar concentration (MAC) has served as the standard measure of potency for volatile anaesthetic agents. It is defined as the minimum alveolar concentration of inhaled anaesthetic at which 50% of people do not move in response to a noxious stimulus.

The minimum alveolar concentration (MAC) is the minimum concentration of an inhaled anesthetic at 1 atm of pressure that prevents skeletal muscle movement in response to a surgical incision in 50% of patients.

Jul 3, 2020 · The measure they derived from the experiment was the minimum alveolar concentration (MAC) or the alveolar concentration of anesthetic at 1 atmosphere, which produces immobility in 50% of subjects exposed to a one-inch skin incision.

Oct 19, 2022 · In 1965, Eger et al. introduced the concept of minimum alveolar concentration (MAC), and it has since been used as the standard measure of potency for volatile anesthetic agents (see Image. MAC Dose Response). Previous attempts to create a measure to determine the adequacy of anesthetic dosin …

The minimum alveolar concentration (MAC) is the alveolar concentration of anesthetic that prevents movement in 50% of subjects in response to a surgical stimulus.

Minimum alveolar concentration (MAC) provides a tar-get-controlled titration and real-time feedback of inhaled volatile anesthetic agent administration. It is defined as the minimum alveolar concentration at sea level of inhaled anesthetic required to prevent apparently purposeful move-ment in 50% of patients in response to a “standardized”

Since its introduction in 1965, minimum alveolar concentration (MAC) has served as the standard measure of potency for volatile anaesthetic agents. It is defined as the minimum alveolar concentration of inhaled anaesthetic at which 50% of people do not move in response to a noxious stimulus.