(A) qPCR analyses of RNAs from undifferentiated (Thy1 +) and differentiated (c-Kit +) spermatogonia (SG), spermatocytes (SC), and round spermatids (RS) to determine the levels of Mga SV (left panel) and canonical Mga (right panel) mRNAs.

A ready-to-use mix for SYBR Green qPCR, containing ROX reference and suitable for all qPCR instruments without adjusting the concentration of ROX. 4 x 1.25 ml (500 rxns/20ul reaction)

Genomic analysis of lung adenocarcinomas has revealed that the MGA gene, which encodes a heterodimeric partner of the MYC-interacting protein MAX, is significantly mutated or deleted in lung adenocarcinomas. Most of the mutations are ...

Jan 30, 2018 · In this study, we have investigated their role in genomic targeting of PRC1.6. ChIP-seq analysis revealed colocalization of MGA, L3MBTL2, E2F6 and PCGF6 genome-wide. Ablation of MGA in a human cell line by CRISPR/Cas resulted in complete loss of PRC1.6 binding.

Here, by performing a CRISPR-based loss-of-function screen in embryonic stem cells (ESCs), we identify PcG gene Mga involved in the repression of endodermal transcription factor Gata6. We report that deletion of Mga results in peri-implantation embryonic lethality in mice.

In this study, we dissect the protein-DNA interactions between Mga and a model category A promoter (P emm) to understand how this process occurs and test whether these findings can be applied to other Mga-regulated promoter binding sites in GAS.

Apr 29, 2024 · Created by the French digital PCR company Stilla, in collaboration with MGA Medtech, the new Nio™+ is a versatile, all-in-one, fit-for-throughput, digital PCR instrument with unparalleled user-friendliness. It is very compact, fast and highly automated.

Mar 7, 2024 · These data show that MGA regulates multiple pro-proliferative pathways in hematopoietic cells and cooperates with the RUNX1::RUNX1T1 fusion oncoprotein to enhance leukemogenesis.

qSTAR qPCR primer pairs against Mus musculus gene Mga

Dec 12, 2006 · We describe a microfluidic genetic analysis system that represents a previously undescribed integrated microfluidic device capable of accepting whole blood as a crude biological sample with the endpoint generation of a genetic profile.