Metachromasia (var. metachromasy) is a characteristic change in the color of staining carried out in biological tissues, exhibited by certain dyes when they bind to particular substances present in these tissues, called chromotropes.

Metachromasia is a disorder in which certain stains cause cells and tissues to change color significantly from the pigment complex's original color. You might find these chapters and articles relevant to this topic.

Oct 27, 2020 · The significance of green metachromasia to Toluidine blue O, exhibited by vitelline cells of monogeneans and epicuticle of millipedes is elucidated, as due to phenolacid mucopolysaccharide...

1 day ago · The meaning of METACHROMASIA is the property of various tissues of staining in a different color (as when treatment with a blue aniline dye makes a cellular element red).

Metachromasia may be defined as the staining of tissue elements in two colors from a solution of a single dye. The phrase “a solution of a single dye” in this context means a solution of a single chemical compound.

In the present study, to justify this critical stance, we demonstrate that pH of the staining solution, the use of dehydration, and time influence the specificity and intensity of toluidine blue and the metachromatic staining of chondrogenesis in vitro and cartilaginous matrix in vivo.

Metachromasia takes place when certain negatively charged groups on the tissue react with cationic dyes. On polymerization the original colour of the dye changes to another colour (eg mast cell stain pink with toluidine blue).

Jul 11, 2024 · Metachromasia refers to the phenomenon where a tissue component stains in a different color from that of the dye used. This can result in yellow hues when a red dye is used, or purple to red shades when a blue dye is used.

Metachromasia (also known as metachromacy) is a characteristic color change which certain aniline dyes exhibit when bound to particular substances or when concentrated in solution. For example, the basic dye toluidine blue becomes distinctly pink when bound to cartilage matrix.

1. failure to stain true with a given stain. 2. the different coloration of different tissues produced by the same stain. 3. change of color produced by staining. adj., adj metachromat´ic. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc.