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  1. Copilot Answer
    Styling

    The W221 S-Class' exterior styling is distinctly different from the W220. The W220 somewhat broke with … See more

    Features

    Like for all other S-Class generations, the W221 introduced a raft of improved and new features and systems. The standard COMAND now also controlled more of these features and/or provided access to additional s… See more

    Models

    Development to further refine the W221 started in 2006 with these design changes being approved in early 2007. The revised 2010 S-Class was announced on April 8, 2009, at Stuttgart. The minor model update includes mi… See more

    Specifications

    S 280 is only sold in the United Kingdom, Ireland and Asia (badged as S 300).
    S 350 CDI 4MATIC is badged as S 350 CDI 4MATIC BlueEFFICIENCY in Germany.
    S 500 is badged as S 550 in Canada, US and Japan … See more

    Marketing

    As part of the W221 launch campaign, Mercedes-Benz Accessories GmbH introduced a series of 17 products under S-Class Collection, beginning in 2005–09. Products include a wrist watch designed with Sindelf… See more

    Awards

    In the 2007 J.D. Power Initial Quality Study, the W221 tied for first ranking in its category (with the Audi A8) for having the fewest quality problems in the industry after 90 days of ownership. The W221 was given the Bild a… See more

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