As has been found for other types of tumors, there is increasing evidence that myeloid-derived suppressor cells (MDSCs) play important roles in the promotion and progression of LC. Here, …

In this study we tested possible contributions of MDSC to the development of lung cancer using two experimental models: a lung cancer model in CC10 transgenic mice (CC10Tg), and a lung …

Myeloid-derived suppressor cells (MDSC) are widely implicated in immune suppression associated with tumor progression and chronic inflammation. However, very little is known …

Oct 7, 2021 · Myeloid-derived suppressor cells (MDSCs), characterized by their suppressive effects on immune responses, are important motivators to promote tumor immune escape. …

Jan 15, 2021 · Myeloid-derived suppressor cells (MDSCs) suppress antitumor immune activities and facilitate cancer progression. Although the concept of immunosuppressive MDSCs is well...

Nov 23, 2020 · Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that proliferate in the setting of cancer and have potent …

We aimed to investigate the presence of MDSC subtypes and of interleukin-8 (CXCL-8) in the peripheral blood in lung cancer subtypes including non-small cell lung cancer (NSCLC) and …

Myeloid-derived suppressor cells (MDSC) are one of the major factors limiting the efficacy of immune therapy. In a clinical trial of patients with extensive stage small cell lung cancer …

Jul 24, 2024 · IRF8 promotes MDSC formation in lung adenocarcinoma which lacks experimental verification, especially since IRF8 regulates MDSC differentiation through the IL6-JAK-STAT3 …

Apr 26, 2019 · Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of immune cells from the myeloid lineage. MDSCs expand in pathological situations, such as chronic …