MBIP Gene - GeneCards | MBIP1 Protein | MBIP1 Antibody
Mar 30, 2025 · Enables identical protein binding activity and protein kinase inhibitor activity. Involved in several processes, including positive regulation of JNK cascade; regulation of cell division; and regulation of macromolecule metabolic process. Located in …
Systemic gene transfer of binding immunoglobulin protein (BiP) prevents ...
Jan 2, 2015 · In this study we investigated the therapeutic potential of in-vivo lentiviral vector delivery of the murine BiP transgene (Lenti-mBiP) compared with the control green fluorescent protein (GFP) transgene in the mouse model of CIA.
MBIP (MAP3K12 binding inhibitory protein) drives NSCLC ... - Nature
Sep 22, 2020 · We functionally characterized that MBIP mediates activation of the JNK pathway and induces expression of matrix metalloproteinases (MMPs), which are necessary for the invasive and metastatic...
MBIP promotes ESCC metastasis by activating MAPK pathway
A total of 1.5×10 6 KYSE150 cells with empty vector (NC) or MBIP overexpression (MBIP-WT) were injected into the tail vein of mice. Approximately 45 days later, mice were scanned using a small-animal 18 FDG PET/CT (Inviscan, IRIS).
MBIP is sufficient to drive proliferation, migration and invasion of ...
Representative images of (d) transwell chamber assays performed for migration and invasion or (e) 3D matrix (Matrigel + collagen) with invasive spheroids, formed by i393P and iH157 cells with...
The leucine zipper-like motifs of MUK are essential for MBIP …
Mitogen-activated protein kinase upstream kinase/dual leucine zipper-bearing kinase/leucine-zipper protein kinase (MUK/DLK/ZPK) is a MAPKKK class protein kinase that induces JNK/SAPK activation. We...
MBIP ORF Vector - Amerigo Scientific
The MBIP ORF Vector holds the gene (cloned by a restriction enzyme-independent method) between an AflII and EcoRV cut site. Inserts are flanked by and can be excised using AflII and …
MBIP Protein Overview - Sino Biological
Know comprehensive MBIP protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction.
Entry - *609431 - MAP3K12-BINDING INHIBITORY PROTEIN; MBIP …
Northern blot analysis detected a 1.8-kb MBIP transcript in all tissues examined, with relatively high expression in heart and lung. MBIP localized in several nuclear patch-like structures following overexpression in COS-1 cells.
MAPK Upstream Kinase (MUK)-binding Inhibitory Protein, a …
Jul 14, 2000 · Mitogen-activated protein kinase upstream kinase/dual leucine zipper-bearing kinase/leucine-zipper protein kinase (MUK/DLK/ZPK) is a MAPKKK class protein kinase that induces JNK/SAPK activation. We report here a protein named MBIP that …
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