Diagnostic approach to suspected TTP, HUS, or other ... - UpToDate
The initial evaluation of a patient with suspected thrombotic thrombocytopenic purpura (TTP) or another primary thrombotic microangiopathy (TMA) syndrome must focus on distinguishing …
疑似TTP、HUS或其他血栓性微血管病的诊断方案 - UpToDate
对于疑似血栓性血小板减少性紫癜(thrombotic thrombocytopenic purpura, TTP)或其他原发性血栓性微血管病(thrombotic microangiopathy, TMA)综合征的患者，初始评估必须侧重于将这些原 …
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Thrombotic microangiopathies (TMAs) are potentially life-threatening conditions caused by small-vessel platelet thrombi. Characteristic clinical features are microangiopathic hemolytic anemia …
Likely causes of MAHA and thrombocytopenia - UpToDate
TMA: thrombotic microangiopathy; MAHA: microangiopathic hemolytic anemia; DIC: disseminated intravascular coagulation; HELLP: hemolysis, elevated liver function tests, low platelets; TTP: …
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This differs from thrombotic thrombocytopenic purpura (TTP), which can be diagnosed using an ADAMTS13 assay and is rarely associated with AKI. This topic discusses our approach to the …
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Mar 24, 2025 · TTP can be immune-mediated, due to autoantibodies against ADAMTS13, or hereditary, due to pathogenic variants in the ADAMTS13 gene. This topic reviews the clinical …
TTP和其他原发性TMA的病理生理学 - UpToDate
免疫性血栓性血小板减少性紫癜(thrombotic thrombocytopenic purpura, TTP)是原发性TMA中最早得到阐释的疾病，通过免疫性TTP也许最能了解TMA的病理生理学。在原发性TMA中，TTP是 …
Immune TTP: Treatment of clinical relapse - UpToDate
Jun 24, 2024 · It is characterized by small-vessel platelet-rich thrombi, thrombocytopenia, and microangiopathic hemolytic anemia (MAHA). Some patients may have neurologic …
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其特征为小血管内产生富血小板血栓，引起血小板减少、微血管病性溶血性贫血(microangiopathic hemolytic anemia, MAHA)，有时还会引起器官损伤。TTP必须立刻治疗，否则死亡率接 …
TMA syndromes and other systemic disorders - UpToDate
Thrombotic thrombocytopenic purpura (TTP) May have severe neurologic abnormalities. Inherited; may present in a newborn infant, a child with thrombocytopenia, or, less commonly, …