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Learn more about Bing search results hereMucin proteinOrganizing and summarizing search results for youWikipediahttps://en.wikipedia.org/wiki/Mucin_4Mucin 4 - WikipediaMucin-4 (MUC-4) is a mucin protein that in humans is encoded by the MUC4 gene. [3] Like other mucins, MUC-4 is a high-molecular weight glycoprotein. [4]The major constituents of mu…Wikipediahttps://en.wikipedia.org/wiki/MucinMucin - WikipediaFour of these occur in a well-conserved gene cluster (at 11p.15.5 in humans). [15] The EGF-like domain containing mucins. These include MUC3(A,B), MUC4, MUC12, MUC13, and MUC17. [1…
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See all on WikipediaMucin 4 - Wikipedia
Mucin-4 (MUC-4) is a mucin protein that in humans is encoded by the MUC4 gene. Like other mucins, MUC-4 is a high-molecular weight glycoprotein. The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated … See more
MUC4 is an O-glycoprotein that can reach up to 2 micrometers outside the cell. MUC4 mucin consists of a large extracellular alpha … See more
Pancreatic
MUC4 is often overexpressed in pancreatic adenocarcinomas and has been shown to promote tumor growth and metastasis, though the mechanism by which it does so is not known. MUC4 detection is … See moreNormal
In normal functioning, MUC-4 is known to play anti-adhesive roles in the body, such as in lubricating the reproductive lining. It is also found in the respiratory tract - particularly in the trachea and lung - and the See moreMUC-4 is also relevant to several other disease conditions. Polymorphisms in the MUC4 gene have been found to play a role in the progression of endometriosis and related infertility, … See more
Wikipedia text under CC-BY-SA license MUC4 Gene - GeneCards | MUC4 Protein | MUC4 …
Mar 30, 2025 · MUC4 (Mucin 4, Cell Surface Associated) is a Protein Coding gene. Diseases associated with MUC4 include Biliary Tract Cancer and Pancreatic Adenocarcinoma. Among its related pathways are O-linked …
Structure, evolution, and biology of the MUC4 mucin - PMC
MUC4, a member of transmembrane mucin family, is expressed in airway epithelial cells and body fluids like saliva, tear film, ear fluid, and breast milk. In addition to its normal expression, an …
4585 - Gene ResultMUC4 mucin 4, cell surface associated [ (human)]
The human mucin gene MUC4 is overexpressed in pancreatic cancer and cancer cell lines, while remaining undetectable in the normal pancreas, indicating its important role in pancreatic …
The MUC gene family: Their role in diagnosis and early detection …
Mucins (MUCs) are heavily glycosylated, high molecular weight glycoproteins with an aberrant expression profile in various malignancies. This review considers briefly the potential use of …
MUC4 as a diagnostic marker in cancer - PubMed
MUC4, a membrane-bound mucin encoded by a gene located on chromosome locus 3q29, is aberrantly expressed in several cancers including those of the bile duct, breast, colon, …
- Author: Subhankar Chakraborty, Maneesh Jain, Aaron R Sasson, Surinder K Batra
- Publish Year: 2008
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MUC4 mucin 4, cell surface associated [Homo sapiens (human)] - Gene …
Feb 8, 2025 · Genetic variants of MUC4 are associated with susceptibility to and mortality of colorectal cancer and exhibit synergistic effects with LDL-C levels.
MUC4 Gene: Function, Expression, and Role in Cancer
MUC4 is a membrane-bound mucin, a type of highly glycosylated protein that forms a major component of mucus, the viscous substance covering epithelial surfaces. MUC4 plays a …
MUC4 mucin- a therapeutic target for pancreatic ductal …
Studies demonstrating that abrogation of MUC4 expression reduces proliferation and metastasis of PC cells and enhances sensitivity to therapeutic agents affirm its utility as a therapeutic …
MUC4 (mucin 4, cell surface associated)
Feb 1, 2007 · MUC4 gene is located on the chromosome 3 in the region q29, oriented from telomere to centromere and clustered with another mucin gene MUC20. MUC4 is highly polymorphic, harboring numerous sequences …
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