021614 B6.Cg-Tg(S100A8-cre,-EGFP)1Ilw/J These MRP8-Cre-ires/GFP transgenic mice may be useful in studies utilizing "Cre-lox" technology or fluorescent protein expression in …

Dec 4, 2024 · Here, we report that a single allele of the Mrp8-cre/ires-eGFP transgene predisposes mice to CAIA, likely due to the interfered expressions of genes close to the …

Jan 21, 2020 · MRP8-Cre mice express the Cre recombinase followed by an IRES-GFP reporter gene. This allows detection of GFP at low levels in neutrophils by flow cytometry (6, 95). …

The MRP8-Cre-ires/GFP transgene was designed to place a Cre recombinase gene, internal ribosomal entry site (IRES), and an enhanced green fluorescent protein (EGFP) gene all …

Mar 7, 2025 · LSL-Sting1 N153S/+ Mrp8-cre mice exhibited reduced body weight and overall survival compared with littermate cre − controls (Fig. 2, A and B). These mice also developed …

Mar 28, 2017 · Mice hemizygous for the MRP8-Cre-ires/GFP transgene are viable and fertile, with the human S100 calcium binding protein A8 (calgranulin A) (MRP8 or S100A8) promoter …

Here, we report that a single allele of the Mrp8-cre/ires-eGFP transgene predisposes mice to CAIA, likely due to the interfered expressions of genes close to the insertion site. These ndings...

Jan 6, 2025 · frequently investigated using MRP8-Cre mice to generate neutrophil-specific knockouts. Recent study demonstrated that MRP8-Cre mice have off-target deletions in …

Jan 7, 2025 · Recent study demonstrated that MRP8-Cre mice have off-target deletions in Serpine1 and Ap1s1 genes. Serpine1, encoding plasminogen activator inhibitor-1, is a key anti …

MRP8-Cre-IRES/GFP is a genetically engineered mouse strain that expresses Cre recombinase under the control of the MRP8 (macrophage-related protein 8) promoter, along with an internal …