A selected-ion monitoring (SIM) chromatogram is similar to an EIC/XIC, with the exception that the mass spectrometer is operated in SIM mode, such that only preselected m/z values are detected in the analysis. [5] SIM experiments can be performed using mass spectrometry (MS) or tandem mass spectrometry (MS/MS) instruments.

Selected reaction monitoring (SRM), also called multiple reaction monitoring (MRM), is a method used in tandem mass spectrometry in which an ion of a particular mass is selected in the first stage of a tandem mass spectrometer and an ion product of a fragmentation reaction of the precursor ions is selected in the second mass spectrometer stage ...

Jun 1, 2009 · A simple, sensitive, and rapid quantitative LC-MS/MS assay was designed for the simultaneous quantification of free and glycoprotein bound monosaccharides using a multiple reaction monitoring (MRM) approach.

Dec 13, 2023 · 提取离子色谱图（EIC或XIC） 英文全称为：Extracted Ion Chromatogram。它指的是特定质荷比下的色谱图，即m/z固定，横坐标为保留时间，纵坐标为强度。图1中每一种颜色的图就表示一个EIC (XIC) 图。

It is an optimized workflow for generating HRMS XIC (or ion mobility XICs) trace(s) and performing quantitation analogous to a SIR (single ion recording) or MRM (multiple reaction monitoring) type workflow.

Jan 19, 2016 · MRM delivers a unique fragment ion that can be monitored and quantified in the midst of a very complicated matrix. SRM plots are very simple, usually containing only a single peak. This characteristic makes the MRM plot ideal for sensitive and specific quantitation.

The typical extracted-ion chromatograms (XIC) of MRM chromatograms of standards and samples obtained are shown in Fig. ...

All the analytes containing IS (verapamil) were detected without interference in the multiple-reaction monitoring (MRM) mode with positive electrospray ionization.

Download scientific diagram | Representative extract ion chromatograms (XIC) of multiple-reaction monitoring (MRM) chromatograms of the 35 investigated constituents.

MRM XIC comparison between SCIEX 7500 System (left) and QTRAP 6500+ LC-MS/MS System (right) for mAb signature peptides at 5 or 39 fmol/mL in rat plasma. also a wide linear dynamic range (LDR) combined with high reproducibility to provide reliable quantitative measurements.