Exploring the role of ITGB6: fibrosis, cancer, and other diseases
Dec 21, 2023 · MMP is a key gene associated with cancer disease progression, invasion, metastasis, and avoidance of immune surveillance and is frequently upregulated in cancer. …
Inhibition of ITGB1 enhance the anti-tumor effect of cetuximab in ... - LWW
Jul 2, 2020 · In this study, we firstly established a cell model of ITGB1 inhibition or overexpression in LS174T cells, and found that inhibition of ITGB1 could enhance the inhibition effect of …
Expression profiling using a cDNA array and ... - PubMed
Mar 4, 2014 · The overexpression of the matrix extracellular genes ITGA-3 and ITGB-5 is associated with advanced stage tumors, and the genes MMP-2 and MMP-9 are …
ITGB1 and DDR activation as novel mediators in acquired ... - Nature
Jan 4, 2024 · For the present study, we explored the role of MEK/MAPK and ITGB1 levels contributing to osimertinib resistance in EGFR mutant NSCLCs and we assessed whether …
High expression of integrin β6 in association with the Rho–Rac …
May 17, 2016 · The increased regional and distant metastasis observed in HER 2+ tumors with high levels of ITGB 6 might be mediated by the canonical Rho–Rac pathway through …
Expression Profiling Using a cDNA Array and …
Mar 4, 2014 · This investigation intended to evaluate the association between FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 gene and protein expression levels in tumor tissue with clinical …
β2 integrin regulates neutrophil trans endothelial migration …
Feb 8, 2025 · Our comprehensive analysis of the molecular landscape surrounding the trauma in TBI mice has revealed a significant alteration in the abundance of β2 integrin (ITGB2), …
MAPK activity and cross-signaling between Mmp14, Erk and Itgb1 …
MAPK activity and cross-signaling between Mmp14, Erk and Itgb1 are involved in branching morphogenesis. (A) Silencing Mmp14 reduces Erk activity and the level of Itgb1. (i) …
Distinct Expression Patterns of Genes Coding for Biological …
Nov 27, 2022 · Expression of the SMAD-6 gene was significantly increased and the expression of the LOX, CAV-1, PLG, ITGA-2, MMP-1, and CTGF genes was significantly decreased in CHC …
Matrix metalloproteinases: Master regulators of tissue …
Jan 15, 2025 · Matrix metalloproteinases (MMPs) control the complex processes of morphogenesis and tissue remodelling. They are important for both homeostatic and …