The CGE is a fusion of the rostral medial and lateral ganglionic eminence, which begins at the mid to caudal thalamus. There are two molecular domains that exist within the CGE and closely resemble extensions of the caudal MGE and LGE. [9] The CGE is distinct from the LGE and MGE in gene expression patterns and progeny produced.

Nov 4, 2021 · The GE is anatomically subdivided into the medial ganglionic eminence (MGE), the lateral ganglionic eminence (LGE) and the caudal ganglionic eminence (CGE), in which the MGE and LGE develop into...

In the forebrain, neuronal diversity within the ventral telencephalon is associated with specific transient germinal zones, termed the medial, caudal and lateral ganglionic eminences (MGE, CGE, and LGE, respectively).

大量的研究证实，中间神经元起源于位于腹侧端脑的 神经节隆起 （GE, ganglionic eminence）。神经节隆起根据解剖位置的不同，又可以分为内侧（MGE）、外侧（LGE）和尾侧神经节隆起（CGE）。在本研究中，研究人员收集了人类妊娠期9-18孕周的神经节隆起样品，系统 ...

Nov 4, 2002 · Through gene expression studies, in vitro migration assays, genetic mutant analysis and in vivo fate mapping in mice, we found that the CGE is a progenitor region that is distinct from both the...

Apr 22, 2009 · Our analysis, based on gene expression array data, followed by in situ hybridization, provides a nearly comprehensive description of the TFs expressed in stem/progenitor cells and their derivatives of the embryonic day (E) 15.5 MGE and CGE in mice with different dosages of Dlx1&2 and Mash1.

Cortical interneuron diversity largely emerges from spatially segregated progenitor cells with distinct transcriptional profiles. The schema shows the main sources of cortical interneurons, CGE, MGE and POA, which contain progenitor cells that can be (more...)

Feb 3, 2010 · By combining an inducible genetic fate mapping strategy with electrophysiological analysis, we have systematically characterized the populations of cortical GABAergic interneurons that originate from the caudal ganglionic eminence (CGE).

MGE and CGE-derived INs typically coexpress a combination of different neurochemical markers, some of which are illustrated. The germinative regions are divided into a ventricular zone (VZ) and a subventricular zone (SVZ), each hosting distinct neural precursors or progenitors.

Mar 5, 2018 · Cortical inhibitory neurons are a diverse population that varies widely in morphology, connectivity and patterns of activity 1. This group of neurons is developmentally derived from...