In this study, we compared the expression levels of MX2 gene between a new set of narcolepsy subjects and age-, sex-, and HLA genotype-matched control subjects, as well as HLA …

Jul 18, 2013 · The main function of HLA class I gene products (HLA-A, -B, and -C) is to present endogenous peptides to responding CD8+ T Cells while the class II coded molecules HLA-DR, …

CTCF depletion by RNAi resulted in a substantial reduction in HLA-DRB1 and HLA-DQA1 gene expression. These data suggested that CTCF and potentially XL9 were critical for expression …

One of the approaches to decrease the costs of iPSC-derived therapies is the use of allogenic homozygous human leukocyte antigen (HLA)-matched donors to generate iPSC lines and to …

We present a highly sensitive and specific tool for quantifying donor-specific memory B cells in peripheral blood of individuals using cell lysates covering the complete HLA class I and class II …

Major histocompatibility complex class II (MHCII) molecules play a pivotal role in the immune system because they direct the development and activation of CD4(+) T cells. There are three …

Here, we present a novel ELISPOT assay for quantifying HLA class II-specific memory B cells from peripheral blood. This technique provides a unique tool for monitoring the HLA class II …

Mouse MHC gene complex called H-2. Human MHC gene complex called HLA. Definitions: Alleles functional forms of the same genes. Heterozygous different allele at each locus. …

The major histocompatibility complex (MHC) genes, coding for the histocompatibility leukocyte antigens (HLAs) are located on the short arm of chromosome 6. The HLA gene products are …

Nov 1, 2018 · We developed a novel HLA-specific B-cell FluoroSpot assay capable of enumerating multiple HLA-specific Antibody Secreting Cells (ASC) originated from circulating …