(A) The representative insets of immunofluorescent of Iba1, GFAP, and STING in the cortex and hippocampus at 3 days (3d) and 7 days (7d) after tMCAO, related to Figure 1E.

Mar 30, 2025 · STING1 (Stimulator Of Interferon Response CGAMP Interactor 1) is a Protein Coding gene. Diseases associated with STING1 include Sting-Associated Vasculopathy, Infantile-Onset and Sting-Associated Vasculopathy With Onset In Infancy. Among its related pathways are Cytosolic sensors of pathogen-associated DNA and SARS-CoV-2 Infection.

Oct 5, 2023 · Stimulator of interferon genes (STING) is a hub of cytosolic DNA sensing. STING is activated by cyclic dinucleotides synthesized by bacteria or in cells by cyclic GMP-AMP synthase (cGAS) after binding foreign or self-DNA.

The DNA-sensing receptor cyclic GMP-AMP synthase (cGAS) and its downstream effector Stimulator of Interferon Genes (STING) sense foreign and self-DNA and trigger type I Interferon (IFN) immune ...

Myelin basic protein (MBP) citrullination by peptidylarginine deiminase (PAD) enzymes leads to incomplete protein-lipid bilayer interactions and vulnerability to proteolytic enzymes, resulting in disorganization of the myelin sheath in the central nervous system.

Mar 1, 2011 · In the present study, we investigate the ability of MBP to tether microtubules to lipid bilayers and to actin filaments in vitro, and the effects of post-translational modifications to MBP on these interactions.

Dec 14, 2020 · I have been using my 2010 iMac as target display with my 2017 MBP 15", it works well and reliably. I use a OWC Thunderbolt 3 dock to interface with several HDD as well.

Nov 15, 2012 · Patients with white matter disease on magnetic resonance imaging had elevated titers of antibodies to both MBP and PLP at 30days after stroke, and anti-MBP antibodies were associated with worse outcome.

Jan 8, 2020 · Myelin basic protein (MBP) is the second most abundant protein in central nervous system myelin. Since the 1980s, it has been regarded as a marker of brain tissue injury in both trauma and disease. There have been no recent reports regarding MBP in aneurysmal subarachnoid haemorrhage (SAH).

In conclusion, some wasp venom peptides, particularly phospholipase A1, may potentially act as the molecular motifs of the human 3HLA-DR2b-associated immunodominant MBP88-93, and possibly present a mechanism for induction of wasp sting-associated ADEM.