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MBL belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL recognizes …

Jul 19, 2023 · Monoclonal B-cell lymphocytosis (MBL) is estimated to affect about 5–12% of people. It doesn’t cause symptoms and doesn’t require active treatment. A subtype called high …

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Apr 9, 2019 · We subjected mice with double (MBL −/−) or single (MBL-A −/− or MBL-C −/−) MBL isoform depletion to transient middle cerebral artery occlusion (tMCAo). MBL −/− mice had …

4 days ago · MBL is a condition where there is an accumulation of abnormal B-cells in the blood. B-cells, also known as B-lymphocytes, are a type of white blood cell that makes antibodies to …

Dec 23, 2001 · Mannan‐binding lectin (MBL) is a C‐type lectin (a lectin showing calcium‐dependent carbohydrate binding) with the carbohydrate recognition domains (CRDs) …

MBL has opsonic activity and, in cooperation with MBL-associated serine proteases (MASPs), the ability to activate complement via the lectin pathway. Mannan-binding lectin belongs to the …

Sep 6, 2013 · Mannose-binding lectin (MBL), a plasma C-type lectin, plays an important role in innate immunity. However, the interaction, and the consequences of it, between MBL and the …

Rat monoclonal antibodies (MoAbs) against mouse mannan-binding lectin (MBL)-A and MBL-C were generated and assays for MBL-A and MBL-C were constructed. This allowed for the …