Hence, in this study we aimed to assess the association of baseline serum granzyme B, as well as germline variation of the GZMB gene, with clinical outcome to programmed cell death …

First, increased levels of Gzms have been found in the serum (GzmB), plasma (GzmA, GzmB), synovial fluid (GzmB, GzmM), and synovial tissue (GzmK) of patients with RA. Moreover, …

Mar 10, 2022 · In this manuscript, we detailed the latest reports describing the control of IL-10, TGFβ, and GZMB production in different Breg subsets at the molecular level.

Nov 2, 2023 · RNA-seq analysis showed that the DEGs between KHYG1 with short-term re-expression of PRDM1 and control cells overlapped with DEGs between PRDM1 KO vs WT NK …

In the presence of MAF-CM, activated/non-naïve CTLs displayed dysregulated ERK1/2 and NF-κB signaling, impeded CD69 and granzyme B production, impaired killing activity, and …

Mar 11, 2022 · In this manuscript, we detailed the latest reports describing the control of IL-10, TGFb, and GZMB production in different Breg subsets at the molecular level.

Apr 8, 2024 · Primary GC in a TCGA stomach cancer dataset was evaluated for signature expressions, and a log-rank test determined overall survival (OS) and the disease-free interval …

Jul 2, 2015 · Using Maf‐deleted CD8 T cells, our data show the partial dependence on Maf of the TGFβ inhibitory effects on naïve CD8 T‐cell proliferation, IL‐2 production, and Gzmb …

Jun 1, 2020 · Inconsistence in Gzmb and Maf expression might result from the difference between human Th17/1 cells and mouse pathogenic Th17 cells. In addition, as Th17/1 cell …

Super-enhancer profiling identified novel genes that func-tionally specify the CD56dimand CD56brightsubsets, including G-coupled protein receptors (G-PCRs), which may modulate …