Mar 15, 2017 · Here we report that methylation at the 6 position of adenosine (m6A) in RNA is rapidly (within 2 min) and transiently induced at DNA damage sites in response to ultraviolet …

Mar 23, 2017 · Here we report that methylation at the 6 position of adenosine (m 6 A) in RNA is rapidly (within 2 min) and transiently induced at DNA damage sites in response to ultraviolet …

Our results now demonstrate that methylation of poly (A) + RNA occurs in response to UV irradiation, suggesting an unprecedented RNA-mediated response to DNA damage. We next …

Apr 25, 2024 · The profound role of m6A modification in facilitating the response and repair of UV-induced DNA damage has been comprehensively explored. 48 Compelling research indicates …

In this review, we summarize the recent advances in the regulation and function of m 6 A RNA methylation, with a focus on UV-induced DNA damage response and the circadian clock …

Feb 2, 2023 · In this review, Sendinc and Shi discuss the recent appreciation of nuclear roles for m6A in regulating chromatin states and gene expression, as well as the recent discoveries of …

Apr 5, 2017 · Ultraviolet (UV) irradiation caused rapid and transient methylation at the 6 position of adenosine (m 6 A), predominantly in 5′ untranslated regions of poly (A) + RNA, including in …

May 18, 2017 · Recently, Yang Xiang and colleagues have reported a novel role for RNA methylation (m6A) in the ultraviolet-induced DNA damage response. Here we’ll summarize …

Apr 30, 2017 · Major finding: m 6 A RNA methylation rapidly recruits Pol κ to UV-induced damage sites to facilitate DNA repair. Concept: UV damage–induced m 6 A methylation of poly (A) + …

Aug 9, 2021 · We uncover heavy but selective m6A deposition on nascent RNAs produced by transcription regulatory elements, including promoter upstream antisense RNAs and enhancer …