The role of m6A modification in the biological functions and
Feb 21, 2021 · We propose that m6A RNA methylation process offer potential targets for cancer therapy in the future. Epigenetics is a discipline that modulates heritable gene expression …
The Emerging Role of m6A Modification in Regulating the …
In this review, we focus on the important role of m6A modification in biological functions and highlight its contributions to immune cells and the development of autoimmune diseases, …
The role of m6A modification in physiology and disease - Nature
Nov 8, 2020 · In this review, we discuss the functions and biological consequences of m 6 A methylation, including physiology and disease, and the prospects for using m 6 A methylation …
m6 A RNA methylation: from mechanisms to therapeutic potential
Feb 1, 2021 · We highlight advances in our understanding of the regulation of m 6 A deposition on mRNA and its context-dependent effects on mRNA decay and translation, the role of m 6 A …
Decoding the interplay between m6A modification and stress …
Nov 15, 2024 · Here, we presented a spatiotemporal m 6 A imaging system (SMIS) that can monitor the m 6 A modification and the translation of mRNAs with high specificity and …
Decoding the m6A epitranscriptomic landscape for …
Jan 18, 2025 · By combining electrical signal features with base alignment data and employing a weighted Noisy-OR probability mechanism, pum6a achieves enhanced sensitivity and …
Recent Advances of m6A Demethylases Inhibitors and Their …
This review focuses on m6A demethylases fat-mass- and obesity-associated protein (FTO) and alkB homolog 5 (ALKBH5), which especially erase m6A modification from target mRNAs. …
RNA m6A methylation across the transcriptome - Cell Press
Feb 2, 2023 · In this review, Sendinc and Shi discuss the recent appreciation of nuclear roles for m6A in regulating chromatin states and gene expression, as well as the recent discoveries of …
The m6A revolution: transforming tumor immunity and enhancing ...
Feb 22, 2025 · Emerging evidence underscores the significant role of m6A modifications in both pro-tumorigenic and anti-tumorigenic immune responses. In this review, we provide a …
The functions and prognostic values of m6A RNA methylation …
N6-Methyladenosine (m6A) is the most common RNA modification and regulates RNA splicing, translation, translocation, and stability. Aberrant expression of m6A has been reported in …