m6A epitranscriptomic regulation of tissue homeostasis during
Apr 6, 2023 · Our study provides a resource for elucidating m6A-mediated mechanisms of tissue aging and reveals a METTL3–m6A–NPNT axis counteracting aging-associated skeletal …
m6A methylation: Critical roles in aging and neurological diseases
Considering the abundance and aging related changes of RNA m6A methylation in CNS, it must play critical roles in aging and degenerative neurological diseases. Altered m6A methylation …
Deciphering RNA m6 A regulation in aging: Perspectives on …
This Perspective article will summarize the current advances in aging-related m 6 A regulation, highlighting the most significant findings and their implications for our understanding of cellular …
Deciphering RNA m6A regulation in aging: Perspectives on …
In this Perspective article, we provide an in‐depth overview of recent advances in m 6 A epitranscriptomic regulation during aging. Specifically, we will focus on the roles and …
Emerging role of RNA m6A modification in aging regulation
May 26, 2022 · The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging. Cell Death Dis. 2021;12(8):744. https://doi.org/10.1038/s41419-021-04016-9 .
m 6A methylation in cellular senescence of age-associated diseases
Jul 3, 2023 · Numerous studies have shown that m 6 A plays an important regulatory role in cellular senescence and aging-related disease. In this review, we systematically summarize …
m6A RNA Modifications in Cellular Senescence – Fight Aging!
Feb 27, 2025 · By modulating RNA stability, splicing, translation, and decay, m6A modifications influence a wide array of biological functions, including cell proliferation, differentiation, and …
Conserved reduction of m6A RNA modifications during aging and ... - PNAS
Jan 16, 2023 · To study the epitranscriptome in the context of cognitive decline, we analyzed the brains of aging mice and human AD patients. During aging, the onset of significant cognitive …
m6A epitranscriptomic regulation of tissue homeostasis during primate aging
How N 6-methyladenosine (m 6 A), the most abundant mRNA modification, contributes to primate tissue homeostasis and physiological aging remains elusive. Here, we characterize the m 6 A …
Frontiers | The Potential Role of m6A RNA Methylation in the Aging ...
Apr 20, 2022 · In this review, we summarise some key findings in the field of m 6 A modification in the ageing process and age-related diseases, including cell senescence, autophagy, …