These investigations show that the Malassezia species causing most skin disease in humans, including the most common cause of dandruff and seborrhoeic dermatitis, is M. globosa (though M. restricta is also involved). [1]

Identification of Malassezia on skin has been aided by the application of molecular or DNA-based techniques. These investigations show that the M. globosa is the species that causes most skin disease in humans, and that it is the most common cause of dandruff and seborrhoeic dermatitis (though M. restricta is also involved). [6]

Skin conditions caused or aggravated by infection by malassezia include: Seborrhoeic dermatitis, dandruff, sebopsoriasis and facial or scalp psoriasis - – most often due to M. restricta and M. globosa. Rarely, invasive pityrosporosis in immunodeficient individuals. How are skin conditions associated with malassezia diagnosed?

Malassezia folliculitis, also known as pityrosporum folliculitis, is an infection of the pilosebaceous unit caused by lipophilic Malassezia yeasts particularly M. globosa, M. sympodialis and M. restricta.

Sequence analysis of the intergenic spacer (IGS1) distinguished specific M. globosa, M. restricta, and M. pachydermatis variants in seborrhoeic dermatitis, atopic eczema, and on healthy skin.

We have shown that Malassezia globosa and M. restricta predominate on dandruff scalp, that oleic acid alone can initiate dandruff-like desquamation, that M. globosa is the most likely initiating organism by virtue of its high lipase activity, and that an M. …

May 15, 2019 · Here, we report on the expression and characterization of the MGL_0310 gene product (CYP61A1), a sterol C-22 desaturase in M. globosa. The open reading frame of the CYP61A1 gene was amplified by PCR from M. globosa CBS 7966 genomic DNA and cloned into a …

Because of the appearance of many drug-resistant strains, new targets have been searched for. Recently, the inhibition of fungal lipases and β-CAs present in these fungi has been proposed as an innovative antidandruff strategy, mainly using M. globosa as a model [167,168].

The Malassezia species mainly identified in pityriasis versicolor lesions are M. globosa and also M. sympodialis and M. furfur. Clinical Presentation. The primary lesions are well demarcated macules, which may be slightly erythematous and covered by fine scales which may only be noticeable after scratching the lesional surface.

Among the 18 different species of Malassezia that have been identified to date, M. restricta and M. globosa are the most predominant fungal species found on human skin. Several studies have suggested a possible link between Malassezia and skin disorders.