
Macrophage colony-stimulating factor - Wikipedia
The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which causes hematopoietic stem cells to differentiate into …
From Monocytes to M1/M2 Macrophages: Phenotypical vs.
Macrophage colony-stimulating factor (M-CSF, also known as CSF-1) and granulocyte-macrophage colony-stimulating factor (GM-CSF) drive the monocyte/macrophage …
Macrophage Colony-Stimulating Factor - ScienceDirect Topics
Macrophage colony-stimulating factor (M-CSF) is a survival, growth, differentiation and activating factor for macrophages and their progenitor cells1, 2. M-CSF is a complex cytokine, which can …
The M-CSF receptor in osteoclasts and beyond - Nature
Aug 17, 2020 · Macrophage colony-stimulating factor (M-CSF) and IL-34 are ligands of CSF1R. CSF1R-mediated signaling is crucial for the survival, function, proliferation, and...
Colony-Stimulating Factors - Holland-Frei Cancer Medicine
Macrophage colony-stimulating factor (M-CSF) is a bone marrow-derived glycoprotein that is capable of supporting the proliferation, maturation, and activation of cells of the mononuclear …
Distinct Properties of Human M-CSF and GM-CSF Monocyte …
Primary human monocytes from healthy donors or SSc patients were differentiated into MDMs in vitro in the presence of GM-CSF (GM-MDM or GM-SSc) or M-CSF (M-MDM or M-SSc) for 6 …
Macrophage colony stimulating factor: not just for macrophages ... - PubMed
Here we review the biology of M-CSF, which has important roles in bone physiology, the intestinal tract, cancer metastases to the bone, macrophage-mediated tumor cell killing and tumor …
Macrophage colony-stimulating factor - Holland-Frei Cancer …
M-CSF stimulates differentiation of progenitor cells to mature monocytes, and prolongs the survival of monocytes. It enhances cytotoxicity, superoxide production, phagocytosis, …
Functions of macrophage colony-stimulating factor (CSF1) in …
Apr 1, 2021 · Macrophage colony-stimulating factor (CSF1) is the primary growth factor required for the control of monocyte and macrophage differentiation, survival, proliferation and renewal.
M-CSF: haematopoietic growth factor or inflammatory cytokine?
Macrophage colony-stimulating factor (M-CSF), initially described as a growth factor of the mononuclear phagocytic lineage, also participates in immunological and inflammatory …