These LysMcre mice may be useful for Cre-lox studies of the myeloid cell lineage (monocytes, mature macrophages and granulocytes) and the innate immune response.

031674 STOCK Lyz2 tm1(cre/ERT2)Grtn /J When these LysM-Cre ER T2 knock-in/knock-out mice are bred with mice containing a loxP -flanked sequence of interest, tamoxifen-inducible, …

When crossing the LysM-Cre mice with two mouse strains with different loxP-flanked targeted genes (β-polymerase and transcription factor RX5), there was a highly efficient gene depletion …

To test the contribution of LysM in sterile acute lung injury, we generated LysM-Cre mice homozygous for the Cre allele (+/+) or wild-type allele (−/−). These mice were challenged with …

In this imaging study, we examined the expression of the LysM and Cdh5 promoters in neonatal and adult mouse retinas and brains under normal conditions and after retinal ischemia …

Nov 8, 2019 · To test the contribution of LysM in sterile acute lung injury, we generated LysMCre mice homozygous for the Cre allele (+/+) or wild-type allele (−/−). These mice were challenged …

Here we report the generation of mice that express Cre in myeloid cells due to targeted insertion of the cre cDNA into their endogenous M lysozyme locus. In double mutant mice harboring …

These LysMcre mice may be useful for Cre-lox studies of the myeloid cell lineage (monocytes, mature macrophages and granulocytes) and the innate immune response.

In 1999, a myeloid-specific Cre-expressing mouse line, LysM-Cre, was generated by Förster and colleagues through directly inserting engineered Cre cDNA into the endogenous lysozyme 2 …

Surprisingly, we found that more than 90% of cells with LysM-Cre mediated recombination in the brain were neurons, rather than myeloid cells, such as microglia. Hence, by using the LysM …