Lymph node stromal cells are essential to the structure and function of the lymph node whose functions include: creating an internal tissue scaffold for the support of hematopoietic cells; the …

Mar 23, 2020 · Non-hematopoietic lymph node stromal cells (LNSCs), made up of both mesenchymal and endothelial cells, are paramount to maintaining LN integrity and function. …

In this review, we will highlight the functional contributions of distinct stromal cell populations during LN development in maintaining immune homeostasis and tolerance and in the …

Oct 1, 2021 · Lymph node stromal cells (LNSCs) not only provide structure to lymphoid organs but can control immune cell activation during health and disease. Novel technologies including …

Lymph node stromal cells (LNSCs) are nonhematopoietic cells (CD45 −) that structure the architecture of the LN, therefore promoting a site-specific environment that favors cell–cell …

LN stromal cells provide the infrastructure necessary to sustain immune cell homeostasis. They direct precise immune cell migration and positioning via spatiotemporal cues. Dynamic …

Lymph nodes (LNs) aid the interaction between lymphocytes and antigen-presenting cells, resulting in adequate and prolonged adaptive immune responses. LN stromal cells (LNSCs) …

Jan 15, 2021 · In this review, we go over recent advances in genetic models and high-resolution transcriptomic analyses that have propelled the finer resolution of the stromal cell …

5 days ago · Development of lymph node stroma models that could answer these questions is under way with spatially organized murine models 24 and human models focused on LECs 25 …

Apr 1, 2017 · Here, we review the function of the major lymphoid stromal cell types; the way they remodel upon inflammation; discuss the available tools to track their behavior; and introduce …