Half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function. IC 50 is a quantitative measure that …

This online calculator is used to determine and graph the IC50 (half maximal inhibitory concentration) value given a set of experimental data. Data can be from Excel or CSV. …

Jul 17, 2015 · Using a logarithmic x-axis (concentration) spreads out the data so the shape of the curve and the quality of the fit are readily visible when the concentrations cover a wide range, …

今天给大家继续分享一个，用GraphPad绘制 IC50 浓度梯度等距排列的技巧。 首先展示一篇 Nature 上的样图。与直接在横坐标上输入0.001, 0.01, 0.1, 1, 10, 100不同的是，X轴上实现浓度 …

The concepts of IC50 and EC50 are fundamental to pharmacology. The EC50 is the concentration of a drug that gives half-maximal response. The IC50 is the concentration of an inhibitor where …

Oct 1, 2024 · IC 50 is the concentration of inhibitor required to bring about 50% inhibition/measurable effect. As we will discuss later, IC 50 is a composite readout of the …

Many log(inhibitor) vs. response curves follow the familiar symmetrical sigmoidal shape. The goal is to determine the IC50 of the inhibitor - the concentration that provokes a response half way …

Jan 25, 2016 · It is possible to calculate IC50 using Excel. The basic equation for IC50 is IC50 = -log10 (x/C), where x is the concentration of your compound and C is the concentration of your...

Prism offers built-in equations designed to handle X values as either concentration OR log (concentration). Be sure you select the correct equation when performing nonlinear …

The simplest estimate of IC50 is to plot x-y and fit the data with a straight line (linear regression). IC50 value is then estimated using the fitted line, i.e., Y = a * X + b, IC50 = (0.5 - b)/a. Log …