Dietary licorice effectively reduced mouse blood Cd by >50% within a month. Licorice intake induced Cd accumulation and Mt1 expression in mice liver. Licorice intake modulated mice gut microbiota and metabolism. Overall dietary licorice substantially improved mice fitness under Cd stress. Highlights

In summary, licorice polysaccharide especially of low molecular weight exhibit anticancer and immunomodulatory activities by suppressing tumor growth and improving general health of mice. They also augment the thymus/spleen index and population of T lymphocytes.

Licorice is a common herb which has been used in traditional Chinese medicine for centuries. This paper provides a summary of the antiviral and antimicrobial activities of licorice. The active components and the possible mechanisms for these activities are summarized in …

Results showed that direct interaction of LG or LQ with C. albicans yeast cells resulted in no growth-inhibition, in vitro. When tested in a murine model of disseminated candidiasis, mice given LQ intraperitoneally before intravenous challenge with live C. albicans yeast cells had similar mean survival times (MST) as untreated mice groups.

In this study, we investigated the effects of hydrophobic flavonoids from Glycyrrhiza glabra LINNE on abdominal fat accumulation and blood glucose level in obese diabetic KK-A (y) mice.

The results showed that T. wilfordii processed with licorice has the anti-inflammatory and immunomodulatory effects on UC mice,and the dose did not show significant hepatotoxicity. Keywords: Tripterygium wilfordii processed with licorice; anti-inflammatory; immune regulation; ulcerative colitis.

Mar 10, 2022 · Dietary licorice effectively reduced mouse blood Cd by >50% within a month. Licorice intake induced Cd accumulation and Mt1 expression in mice liver. Licorice intake modulated mice gut microbiota and metabolism. Overall dietary licorice substantially improved mice fitness under Cd stress.

Dec 3, 2018 · We investigated the effect of three licorice varieties, Glycyrhiza uralensis, G. glabra, and Shinwongam (SW) on a mouse model of inflammation-induced memory and cognitive deficit. C57BL/6 mice were injected with lipopolysaccharide (LPS; 2.5 mg/kg, intraperitoneally) and orally administrated G. uralensis, G. glabra, and SW extract (150 mg/kg/day).

Oct 1, 2024 · Fermented licorice extract significantly alleviated clinical symptoms (P < 0.05), inflammation (P < 0.05), oxidative stress (P < 0.05), and intestinal damage (P < 0.05), while rebuilt the intestinal microbiota in UC mice.

Apr 8, 2020 · In this study, nonpolar licorice extract did not cause mortality or toxicity in mice. Furthermore, the licorice extract did not cause adverse effects on organ weight, serum biochemistry, hematological parameters, or histopathology.