008875 - Lgr5-EGFP-IRES-creERT2 Strain Details - The Jackson …
008875 B6.129P2- Lgr5 tm1(cre/ERT2)Cle /J Heterozygous mice harbor an Lgr5-EGFP-IRES-creERT2 "knock-in" allele that both abolishes Lgr5 gene function and expresses EGFP and …
Lgr5-EGFP-IRES-CreERT2 - 南模生物
将EGFP-IRES-creERT2-WPRE-polyA插入到小鼠Lgr5基因起始密码子处。 应用领域：Cre工具鼠，Lgr5 可作为肠和胃的干细胞的标志基因。 表达细胞类型包括胃腺上皮干细胞、肠的隐窝细胞 …
Lgr5-EGFP marks taste bud stem/progenitor cells in posterior …
Lgr5 (leucine-rich repeat-containing G-protein-coupled receptor 5) has been identified as a marker for adult stem cells in intestine, stomach, and hair follicle; Lgr5-expressing cells give rise to all …
- Author: Karen K. Yee, Yan Li, Kevin M. Redding, Ken Iwatsuki, Robert F. Margolskee, Peihua Jiang
- Publish Year: 2013
Identification of stem cells in small intestine and colon by marker ...
Oct 14, 2007 · Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5, also known as Gpr49) was selected from a panel of intestinal Wnt target genes for its restricted crypt …
- Author: Nick Barker, Johan H. van Es, Jeroen Kuipers, Pekka Kujala, Maaike van den Born, Miranda Cozijnsen, ...
- Publish Year: 2007
Lgr5 -expressing chief cells drive epithelial …
Jun 5, 2017 · Lgr5 marks homeostatic stem cells and ‘reserve’ stem cells in multiple tissues. Here, we report Lgr5 expression in a subpopulation of chief cells in mouse and human corpus glands.
Lgr5-EGFP marks taste bud stem/progenitor cells in posterior …
Lgr5 (leucine-rich repeat-containing G-protein coupled receptor 5) has been identified as a marker for adult stem cells in intestine, stomach, and hair follicle; Lgr5-expressing cells give rise to all …
EGFP expression in an Lgr5-EGFP-IRES-creERT2 knock-in
Here, we describe an intersectional genetic approach that enables cell type-specific targeting of functionally distinct EEC subtypes by combining a newly generated Dre-recombinase …
Fate mapping in mouse demonstrates early secretory …
Jan 9, 2025 · By contrast, the majority of absorptive enterocytes were detected in Lgr5-eGFP negative cells (Figure S4J). These observations suggested that Paneth cells and other secretory cell types arise from Lgr5-expressing cells …
Colonic epithelial-derived FGF1 drives intestinal stem cell ... - Nature
Apr 5, 2025 · Lgr5 + intestinal epithelial-specific deletion of Fgfr2 mice (Lgr5-EGFP-Cre ERT2 Fgfr2 fl/fl) were generated by crossing Lgr5-EGFP-Cre ERT2 recombinase transgenic mice …
The Stem Cell-Expressed Receptor Lgr5 Possesses …
Dec 27, 2013 · Lgr5 is a membrane protein related to G protein-coupled receptors (GPCR)s whose expression identifies stem cells in multiple tissues and is strongly correlated with cancer. Despite the recent identification of endogenous ligands …
