—Leprosy proper, or lepra tuberculosa, in contradistinction to other skin diseases commonly designated by the Greek word lepra (psoriasis, etc.), is a chronic infectious disease caused by the bacillus leprce, characterized by the formation of growths in the skin, mucous membranes, peripheral nerves, bones, and internal viscera, producing ...

leprce are found in the bone marrow in lepromatous leprosy. Fire (1941) found M. leprce in the blood-vessel walls particularly in capillary end loops. Usually the presence of these organisms sets up very little reaction, but sometimes phases of reaction in leprosy occur when there is pain, swelling and redness of digits associated with ...

One very advanced case of leprosy, with abundant B. leprce infiltrating the skin of face, trunk, and limbs, developed acute exfoliating dermatitis and died of pericarditis after two months' illness. Post mortem we were unable to find more than a few granular bacilli, the acute febrile condition having caused almost complete destruction of the ...

Nov 10, 1979 · It is suggested that continuous leakage of bacilli into the circulation from a primary focus of intraneural infection may simultaneously initiate bacillary dissemination and the suppression of cell-mediated immunity. Both these features are essential for the development of lepromatous leprosy.

The normal habitat of the Mycobacterium leprce in the human host is the skin, the nasal mucous membrane and the nerve tissue. Depending upon the type of leprosy one is dealing with, it is possible to demonstrate the causative organism of leprosy in one or other of the three situations mentioned. Briefly, the smears taken from the

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ABSTRACT Experiments were carried out in the skin of patients with leprosy to examine whether suppressor cell populations either exist in the skin of multibacillary leproma- tous leprosy patients, can be activated with antigen, or are induced to emigrate into …

The present study of the chemical components of Badllus leprce has been made in order that a more analytic examination of the immunity-inducing substances present in the micro6rganism may be carried out. We believe that even though the results obtained

GERHARD HENDRIK ARMAUER, HANSEN, the celebrated Norwegian leprologist, was born at Bergen on July 29, 1841. He received his medical education at Christiania and qualified in 1866.

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