Oct 9, 2020 · AstraZeneca’s long-acting antibody (LAAB) combination, AZD7442, will advance into two Phase III clinical trials in more than 6,000 participants at sites in and outside the US that are due to begin in the next weeks.

May 16, 2024 · Positive high-level results from the SUPERNOVA Phase III COVID-19 pre-exposure prophylaxis (prevention) trial showed AstraZeneca’s sipavibart (formerly AZD3152), an investigational long-acting antibody (LAAB), demonstrated a statistically significant reduction in the incidence of symptomatic COVID‑19 compared to control (tixagevimab ...

Aug 20, 2021 · AZD7442, a combination of two long-acting antibodies (LAAB), reduced the risk of developing symptomatic COVID-19 by 77% (95% confidence interval (CI): 46, 90), compared to placebo. The trial accrued 25 cases of symptomatic COVID-19 at the primary analysis.

WILMINGTON, Del., December 8, 2021 – AstraZeneca's EVUSHELD (tixagevimab co-packaged with cilgavimab), a long-acting antibody (LAAB) combination, has received emergency use authorization (EUA) in the US for the pre-exposure prophylaxis (prevention) of COVID-19, with first doses expected to become available very soon.

Oct 11, 2021 · AstraZeneca's AZD7442 long-acting antibody (LAAB) combination achieved a significant reduction in severe COVID-19 or death, according to a statement released today.

Sep 24, 2024 · During COVID-19 pandemic, evidence showed lower immunity after infection and vaccination among immunocompromised individuals. In July 2022, a prophylaxis campaign using long-acting antibodies (LAAB), tixagevimab-cilgavimab was launched in Thailand to decrease hospitalizations among high-risk groups.

Jul 1, 2024 · Sipavibart (formerly AZD3152) is an investigational long-acting monoclonal antibody (LAAB) against COVID-19. Sipavibart was designed to provide broad and potent coverage across Omicron and ancestral viral variants by neutralising spike protein interaction with …

Jan 17, 2023 · Currently there is only one pre-exposure long acting monoclonal antibody (LAAB) available in Canada for the prevention of COVID-19: Evusheld (tixagevimab and cilgavimab). No drug, including Evusheld, is a substitute for vaccination.

Jul 6, 2022 · The Thai Deputy PM, and Public Health Minister, Anutin Charnvirakul, signed an agreement with AstraZeneca Country President, James Teague, to receive 257,500 doses of LAAB for people who suffer from immunodeficiency, to reduce of risk of becoming gravely ill if infected with COVID-19.

Oct 20, 2007 · AstraZeneca's long-acting antibody (LAAB) combination, AZD7442, will advance into two Phase III clinical trials in more than 6,000 participants at sites in and outside the US that are due to begin in the next weeks.