LPS is a major constituent of the cell wall of most gram negative bacteria. It is a highly immunogenic antigen with the ability to enhance immune responses to soluble antigens (1,2). LPS also acts as a specific mitogen for bone marrow derived B lymphocytes from mice (3), rabbits (4), chickens (5), cows (6), hamsters (7), and humans (8).

Purified endotoxin is generally referred to as lipopolysaccharide or LPS, to distinguish it from the more natural complexed cell membrane associated form. The core portion of the polysaccharide chain is common to LPS from wild and mutant bacterial strains.

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This product is phenol extracted from E. coli serotype O111:B4. This LPS serotype has been used to stimulate B-cells22 and induce NOS in human hepatocytes. Bacteria with common serotypes have surface antigens (group O, group H, or LPS) which generate the same antibody response.

List Labs manufactures Lipopolysaccharides (LPS, a.k.a. endotoxin) as reagent grade material, for research use. Learn more about our GMP LPS here.

Oct 16, 2022 · Bacterial endotoxin is the lipopolysaccharide (LPS) present in the cell wall of Gram-negative bacteria. Endotoxin is responsible for inducing fever when introduced in the blood or CSF (cerebrospinal fluid), hence also called, pyrogen.

The LPS for Endotoxin Indicator is composed of E. coli O55:B5 (>100,000 EU/vial) and serves as a stock solution to prepare multiple endotoxin indicators for depyrogenation validation studies. The prepared endotoxin indicators may be tested using reagents from our …

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. A typical LPS molecule has lipid A (a glucosamine-based phospholipid), a relatively short core oligosaccharide and a distal polysaccharide (O-antigen).

Can make multiple endotoxin indicators from one vial; Used for validation studies

The LPS for Endotoxin Indicator is composed of E. coli O55:B5 (>100,000 EU/vial) and serves as a stock solution to prepare multiple endotoxin indicators for depyrogenation validation studies. The prepared endotoxin indicators may be tested using reagents from our …