Feb 10, 2023 · MOOs suppressed mitochondrial damage and the release of tumor necrosis factor-α (TNF-α), interleukin (IL)-6, and IL-1β in astrocytes undergoing LPS stimulation. …

We discovered that MOOs significantly mitigated the pathological damage and decreased the expression of pro-inflammatory cytokines in LPS-induced ALI in mice. Complementary in vitro …

Feb 10, 2023 · There is a potential threshold of MOOs to reverse the interaction between MOOs and LPS in astrocytes, which can be explored in follow-up study. To summarize, we provided …

In vitro, MOOs effectively inhibited the expression of IL-18, IL-1β, and NLRP3 inflammasome in LPS + ATP treated primary rat microglia. We also showed that modulation of NLRP3 …

Sep 24, 2021 · In this study, we investigated whether MOOs can ameliorate depressive-like behaviors in post-stroke depression (PSD) rats and further explored its mechanism by …

Feb 10, 2023 · MOOs suppressed mitochondrial damage and the release of tumor necrosis factor-α (TNF-α), interleukin (IL)-6, and IL-1β in astrocytes undergoing LPS stimulation. …

Then, MOOs promoted autophagosome and lysosome enriched in mitochondria in LPS-stimulated astrocytes. MOOs suppressed mitochondrial damage and the release of tumor necrosis factor …

Morinda officinalis oligosaccharides (MOOs) have anti-depressant properties. In this study, we aimed to determine whether MOOs can improve the symptoms of depression in individuals …

Download scientific diagram | Morinda officinalis oligosaccharides (MOOs) suppress NF‐κB signaling pathway in LPS + ATP treated primary rat microglia.

Dec 1, 2024 · LPS is a classic pro-inflammatory agent and is widely applied to simulate systemic inflammation under stress condition (Yin et al., 2023). LPS-induced mice exhibited prominent …