Le Mans Prototypes were created by the Automobile Club de l'Ouest (ACO). The technical requirements for an LMP include bodywork covering all mechanical elements of the car. As of 2023, there are two classes within Le Mans Prototypes, designated LMP2 and LMP3.

Epstein–Barr virus (EBV) latent membrane protein 2 (LMP2) are two viral proteins of the Epstein–Barr virus. [1] LMP2A/LMP2B are transmembrane proteins that act to block tyrosine kinase signaling.

Jun 26, 2021 · LMP2 cars feature blue backgrounds of the car number panels on the nose and each side of the car; on the mirrors and rear wing endplate; on the LED position-in-class lights on each side of the car; and with a blue “LMP2” decal affixed above the windscreen.

LMP2 is expressed in many EBV-associated malignancies. While its antigenic properties may be useful in developing LMP2-specific immunity, the LMP2A N-terminal motifs also provide a basis to target LMP2A-modulated cellular kinases for the development of treatment strategies.

Oct 6, 2008 · EBV latent membrane protein 2A (LMP2A) provides a surrogate B-cell receptor signal essential for cell survival and is believed to have a crucial role in the maintenance of latency by blocking B-cell activation which would otherwise lead to lytic EBV infection. These two functions demand tight control of LMP2A activity and expression levels.

The Oreca 07 is a Le Mans Prototype built by French manufacturer Oreca to meet the 2017 FIA and ACO LMP2 regulations. [1] It made its official race debut in the opening round of the 2017 IMSA WeatherTech SportsCar Championship, the 24 Hours of Daytona, [3] and its FIA World Endurance Championship debut at the 2017 6 Hours of Silverstone.

Jan 1, 2015 · LMP2 is expressed in various EBV-associated malignancies and likely contributes to their development by inducing cell survival, proliferation, and activation. The LMP2 proteins also induce an immune response, which might help …

We firstly found that LMP2 gene deletion did not cause significantly difference in rats’ daily feeding activity, growth and development as well as blood routine, but it led to metabolic abnormalities including higher levels of low-density lipoprotein cholesterol, uric acid and blood glucose in the LMP2-KO rats.

As the LMP2 inhibitor blocks proliferation of LMP2-rich cancer cells with high specificity, it can now be utilized to determine whether the LMP2 subunit is a valid target for therapeutic intervention in animal models of cancer.

Infection of human B cells with wild-type Epstein-Barr virus (EBV) in vitro leads to activation and proliferation that result in efficient production of lymphoblastoid cell lines (LCLs). Latent Membrane Protein 2 (LMP2) is expressed early after ...