The LMNA gene provides instructions for making several slightly different proteins called lamins. The two major proteins produced from this gene, lamin A and lamin C, are made in most of the …

Jun 12, 2008 · LMNA-related dilated cardiomyopathy (DCM) is characterized by left ventricular enlargement and/or reduced systolic function preceded (sometimes by many years) by or …

Prelamin-A/C, or lamin A/C is a protein that in humans is encoded by the LMNA gene. [5][6][7] Lamin A/C belongs to the lamin family of proteins. Biogenesis of lamin A in normal cells and …

Mar 30, 2025 · LMNA (Lamin A/C) is a Protein Coding gene. Diseases associated with LMNA include Hutchinson-Gilford Progeria Syndrome and Emery-Dreifuss Muscular Dystrophy 2, …

May 24, 2023 · Variants in the gene encoding the nuclear Lamin proteins A and C (LMNA) are estimated to be the second most common cause of familial DCM, second only to TTN …

The human genome has three genes, which code for lamin proteins; LMNA, LMNB1, and LMNB2 [1,17,20,22]. B-type lamins are encoded by the LMNB1 and LMNB2 genes. A-type lamins are …

Mutations in the lamin A/C gene (LMNA) have been associated with several phenotypes ranging from systemic to prevalent of muscle, heart, skin, nerve etc. More recently they have been …

Aug 8, 2017 · The LMNA gene encodes for the intermediate filament proteins lamin A and C. LMNA mutations are associated with a wide spectrum of phenotypes ranging from progeroid …

The LMNA gene consists of 12 exons and encodes the intermediate filament proteins Lamin A and C, which maintain the structural integrity of the nuclear envelope and organize chromatin …

The LMNA gene is like a blueprint for building important parts of our cells. It instructs the body to make proteins called lamin A and C, which are crucial for the structure and stability of a cell's …