CD58, lymphocyte-function antigen 3 (LFA-3), is a glycoprotein that plays a vital role in the body's immune response. The natural ligand to CD58, CD2, is most commonly found on the surfaces …

The glycoprotein CD58, also known as lymphocyte-function antigen 3 (LFA-3), is a costimulatory receptor distributed on a broad range of human tissue cells. Its natural ligand CD2 is primarily …

Lymphocyte function-associated antigen (LFA) −3, also known as CD58, is a 40–70 kDa surface glycoprotein, belonging to a subgroup of cell adhesion molecules. From: Cytokine, 2023

The cell adhesion molecule, lymphocyte function-associated antigen-3 (LFA-3), also known as CD58, plays a central role for naïve and memory T helper cells during the early phase of an …

LFA-3 plays a central role for naive and memory T helper cells during the early phase of an immune response. The LFA-3/CD2 pathway initiates strong antigen-independent cell …

May 15, 1988 · Recently, it has been demonstrated that lymphocyte function-associated Ag (LFA-3) is a natural ligand for CD2 and that this receptor-ligand interaction functions in cell-cell …

In this review Malegapuru Makgoba, Martin Sanders and Stephen Shaw focus primarily on the two molecular pathways of lymphocyte adhesion that have been shown to play a critical role in …

Mar 28, 2025 · Gene structure, promoter characterization, and basis for alternative mRNA splicing of the human CD58 gene. Journal of immunology (Baltimore, Md. : 1950) Wallich R …

Binding of the first region by antibodies allows C02 to respond to subsequent binding of antibody 9-1 and we predict that LFA-3 binding to C02 would allow comparable response to 9-l. If so, the...

3 days ago · CD2, highly expressed on Teff and at lower levels on Treg and naïve T cells (Tn), is an attractive target for depleting Teff at sites of inflammation. SBT115301 is a second …