A kinesin is a protein complex belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases, a type of enzyme).

Jul 19, 2023 · Kinesins are biological motor proteins that are ATP-dependent and function to assist cells with the transport of molecules along microtubules. Simply put, these proteins, function as highways...

There are currently 14 groups and many ungrouped or orphan kinesins. Among these, three kinesins – kinesin-1, kinesin-14 and kinesin-13 – highlight the diverse structure and function of the family. Kinesin-1, the first-discovered kinesin, has been studied extensively.

Oct 11, 2024 · Kinesins are a diverse superfamily of microtubule-based motors that perform fundamental roles in intracellular transport, cytoskeletal dynamics and cell division.

Motile kinesins are motor proteins that move unidirectionally along microtubules as they hydrolyze ATP. The first kinesin was discovered 30 years ago 1,2; since then many more were identified, often based on the sequence conservation of their motor domain (or head).

Molecular motors are enzymes that convert chemical potential energy into controlled kinetic energy for mechanical work inside cells. Understanding the biophysics of these motors is essential for appreciating life as well as apprehending diseases that arise from motor malfunction.

Oct 1, 2009 · Kinesin superfamily proteins (also known as KIFs) are important molecular motors that directionally transport various cargos, including membranous organelles, protein complexes and mRNAs.

Kinesin is a motor protein which uses ATP for energy in order to destabilize or move along the microtubules. It is involved in the transport of the proteins and membrane components from the centre of the cell to the periphery walking towards the positive end of the microtubules known as anterograde transport. Kinesins have also a role in mitosis.

Mar 11, 2025 · Explore how motor proteins like kinesin, dynein, and myosin drive cellular processes through ATP mechanisms and intracellular transport. Motor proteins are essential molecular machines that facilitate movement within cells, playing a crucial role in maintaining cellular function.

Feb 11, 2025 · Kinesin and dynein play key roles in cell division, particularly during mitosis. Kinesin helps assemble and elongate the mitotic spindle, ensuring accurate chromosome distribution. Dynein positions and moves the spindle, aiding chromosome alignment and spindle disassembly during cell division.