Potassium channel subfamily K member 18 (KCNK18), also known as TWIK-related spinal cord potassium channel (TRESK) or K 2P 18.1 is a protein that in humans is encoded by the …

Mar 30, 2025 · KCNK18 (Potassium Two Pore Domain Channel Subfamily K Member 18) is a Protein Coding gene. Diseases associated with KCNK18 include Migraine With Aura 13 and …

Feb 8, 2025 · Altered functional properties of a missense variant in the TRESK K(+) channel (KCNK18) associated with migraine and intellectual disability. The Background K(+) Channel …

Jan 27, 2012 · A loss of function mutation in the TRESK K2P potassium channel (KCNK18), has recently been linked with typical familial migraine with aura. We now report the functional …

Two-pore domain (K2P) potassium channels, such as KCNK18, give rise to background, or leak, potassium conductance, and they regulate diverse cellular functions by adjusting both the …

Our study shows the presence of several KCNK18 gene mutations in both migraine with aura and migraine without aura. However, the precise role of this gene in migraine predisposition …

Gene ID: 445371, updated on 8-Feb-2025. Predicted to enable calcium-activated potassium channel activity; outward rectifier potassium channel activity; and potassium ion leak channel …

Introduction: KCNK18, a potassium channel subfamily K member 18 (MIM*613655), encodes for TWIK-related spinal cord K+ channel (TRESK) and is important for maintaining neuronal …

Clinical resource with information about KCNK18, Migraine, with or without aura, susceptibility to, 13, and available tests. There are links to practice guidelines and authoritative resources like …

Jun 4, 2021 · Here, we report the identification of KCNK18 biallelic missense variants (p.Tyr163Asp and p.Ser252Leu) in a family characterized by three siblings affected by mild-to …