Cafestol and kahweol are natural diterpenes extracted from coffee beans. In addition to the effect of raising serum lipid, in vitro and in vivo experimental results have revealed that the two diterpenes demonstrate multiple potential pharmacological ...

Kahweol is a diterpenoid molecule found in the beans of Coffea arabica and is structurally related to cafestol. [1] Its name derives from the Arabic قهوة qahwa meaning "coffee".

Kahweol is a diterpenoid with formula C20H26O3, isolated from the beans of Coffea arabica. It exhibits antioxidant, anti-inflammatory, anti-angiogenesis and anti-proliferative properties.

Aug 30, 2019 · This review aims to summarize the pharmacological properties and the underlying mechanisms of cafestol-type diterpenoids, which show their potential as functional food and multi-target alternative medicine. Keywords: anti-diabetes; anti-inflammation; anti-tumor; cafestol; kahweol; serum lipid.

Jan 1, 2015 · Kahweol is an antioxidant diterpene present in coffee beans and unfiltered coffee beverages. Since the mid-2000s, many scientific studies have revealed that kahweol is a multitargeted anti-inflammatory bioactive compound with high potential pharmacological interest.

Kahweol and cafestol are two diterpenes extracted from Coffea arabica beans that have distinct biological activities. Recent research describes their potential activities, which include anti-inflammatory, anti-diabetic, and anti-cancer properties, among others.

Kahweol is a compound derived from coffee with reported antinociceptive effects. Based on the few reports that exist in the literature regarding the mechanisms involved in kahweol-induced peripheral antinociceptive action, this study proposed to ...

Kahweol is a natural compound that has multiple anti-inflammatory effects and can inhibit key steps of angiogenesis. It has potential pharmacological indications for preventing or treating inflammatory and angiogenesis-dependent pathologies, including various types of cancer.

Aug 9, 2011 · We show for the first time that kahweol is an anti-angiogenic compound with inhibitory effects in two in vivo and one ex vivo angiogenesis models, with effects on specific steps of the angiogenic process: endothelial cell proliferation, migration, invasion and tube formation on …

Aug 30, 2019 · In humans, cafestol appears to be more effective on elevating serum lipid than kahweol. Meta-analyses of observational researches showed that after daily treatment with 10 mg of cafestol for 4 weeks, serum cholesterol increased by 0.13 mmol∙L −1, while kahweol raised that by 0.02 mmol L −1.