KLRG1 - Wikipedia
KLRG1 is a lymphocyte co-inhibitory, or immune checkpoint, receptor expressed predominantly on late-differentiated effector and effector memory CD8+ T and NK cells. Its ligands are E …
The role of KLRG1: a novel biomarker and new therapeutic target
Jun 19, 2024 · Killer cell lectin-like receptor G1 (KLRG1) is an immune checkpoint receptor expressed predominantly in NK and T-cell subsets that downregulates the activation and …
KLRG1—more than a marker for T cell senescence - PMC
The co-inhibitory receptor killer-cell lectin like receptor G1 (KLRG1) is expressed on NK cells and antigen-experienced T cells and has been postulated to be a marker of senescence. Whilst …
KLRG1 Gene - GeneCards | KLRG1 Protein | KLRG1 Antibody
Mar 30, 2025 · KLRG1 (Killer Cell Lectin Like Receptor G1) is a Protein Coding gene. Diseases associated with KLRG1 include Mastocytosis and Thyroid Dyshormonogenesis 3. Among its …
KLRG1 - BD Biosciences
Killer cell lectin-like receptor G1 (KLRG1) is an immune checkpoint receptor encoded by the KLRG1 gene. It is an inhibitory lectin-like type II transmembrane receptor containing a …
KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All …
Apr 17, 2018 · Our work demonstrates that developmental plasticity of KLRG1 + effector CD8 + T cells is important in promoting functionally versatile memory cells and long-term protective …
The role of KLRG1: a novel biomarker and new therapeutic target
Jun 19, 2024 · Killer cell lectin-like receptor G1 (KLRG1) is an immune checkpoint receptor expressed predominantly in NK and T-cell subsets that downregulates the activation and …
Circulating KLRG1+ long-lived effector memory T cells retain the …
Jun 28, 2024 · KLRG1 + CD8 T cells persist for months after clearance of acute infections and maintain high levels of effector molecules, contributing protective immunity against systemic
KLRG1 killer cell lectin like receptor G1 [ (human)]
Feb 8, 2025 · KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir. KLRG1 is reduced on NK cells in SLE …
Immunoregulatory functions of KLRG1 cadherin interactions are …
KLRG1 is an inhibitory receptor expressed on a subset of mature T and NK cells. Recently, E-, N-, and R-cadherin have been identified as ligands for KLRG1. Cadherins are a large family of …