K v 7.1 (KvLQT1) is a potassium channel protein whose primary subunit in humans is encoded by the KCNQ1 gene. [5] Its mutation causes Long QT syndrome, K v 7.1 is a voltage and lipid …

The KCNQ1 gene belongs to a large family of genes that provide instructions for making potassium channels. These channels, which transport positively charged atoms (ions) of …

Mar 30, 2025 · KCNQ1 (Potassium Voltage-Gated Channel Subfamily Q Member 1) is a Protein Coding gene. Diseases associated with KCNQ1 include Long Qt Syndrome 1 and Jervell And …

Mar 26, 2025 · Title: Genetic characterization of KCNQ1 variants improves risk stratification in type 1 long QT syndrome patients. A mutation in the cardiac KV7.1 channel possibly disrupts …

Apr 30, 2007 · Background— Type-1 long-QT syndrome (LQTS) is caused by loss-of-function mutations in the KCNQ1-encoded I Ks cardiac potassium channel. We evaluated the effect of …

Feb 25, 2025 · Loss-of-function (LOF) pathogenic variants in KCNQ1 encoding a cardiac potassium channel predispose to sudden cardiac death in type 1 congenital long QT syndrome …

Oct 11, 2017 · In this study, we curated from the literature a high-quality set of 107 functionally characterized KCNQ1 variants. Based on this data set, we completed a detailed quantitative …