
Research at Jian Jin Laboratory
Jian Jin laboratory has three main research topics: (1) discover selective inhibitors of histone methyltransferases (HMTs), (2) discover biased ligands of G protein-coupled receptors …
PI | Research at Jian Jin Laboratory
Dr. Jian Jin is currently the Mount Sinai Endowed Professor in Therapeutics Discovery and Director of the Mount Sinai Center for Therapeutics Discovery at Icahn School of Medicine at …
Publications | Research at Jian Jin Laboratory
Jin, J.; Kato, N.; Alteration of the tumor microenvironment by pharmacological inhibition of EZH2 in hepatocellular carcinoma. Int immunopharmacol. 2023, 118:110068. PMID: 37001386.
Jin Lab News | Research at Jian Jin Laboratory
The research team led by Dr. Jian Jin discovered MS147, the first small-molecule degrader of polycomb repressive complex 1 (PRC1) components, BMI1 and RING1B, using the bridged …
Research | Research at Jian Jin Laboratory
The Jin lab has taken a systematic approach to target HMTs for over a decade. By targeting the HMT substrate binding groove, cofactor binding site, and allosteric binding sites, the Menu
Mount Sinai Center for Therapeutics Discovery
Dr. Jian Jin is currently the Mount Sinai Endowed Professor in Therapeutics Discovery and Director of the Mount Sinai Center for Therapeutics Discovery at Icahn School of Medicine at …
PROTACs | Research at Jian Jin Laboratory
Our Novel Degraders Targeting Oncogenic Proteins: MS4077 & MS4078: ALK degrader (PMID: 29627725) MS432: MEK1/2 degrader (PMID:31730343) MS1943: EZH2 degrader …
Members - Research at Jian Jin Laboratory
Group Pictures Department Retreat at NYBG, group picture 2024 Holiday Celebration, December 2024 Holiday Celebration, December 2023 Group Picture, September 2023 Celebration …
2024 | Research at Jian Jin Laboratory - labs.icahn.mssm.edu
The research team led by Dr. Jian Jin and Dr. Wenyi Wei, a Professor at Harvard Medical School, discovered the first-in-class cGAS deubiquitinase-targeting chimeras (DUBTACs), which …
| Research at Jian Jin Laboratory - labs.icahn.mssm.edu
The research team led by Dr. Jin developed a novel technology, termed Acetylation Targeting Chimera (AceTAC), for inducing targeted acetylation of proteins of interest …