There are 2 types of XLP: XLP-1 and XLP-2. People with XLP-1 develop FIM/HLH after Epstein-Barr virus infection. Normally, the Epstein-Barr virus causes a person to develop …

What is X-linked lymphoproliferative (XLP) syndrome? X-linked lymphoproliferative syndrome (XLP), or Duncan’s syndrome, is a rare genetic condition where the immune system does not …

Apr 1, 2019 · People with XLP are healthy until they are exposed to EBV. Then, they can become seriously ill and experience swollen lymph nodes, an enlarged liver and spleen, hepatitis and …

What Is X-Linked Lymphoproliferative Disease? X-linked lymphoproliferative disease (XLP) is a rare genetic disorder that causes the immune system to overreact to infections. It mostly …

X-linked lymphoproliferative syndrome (XLP) is a rare genetic disorder that weakens the immune system, making it difficult for the body to fight off certain viral infections, particularly the …

People with XLP have an increased risk of infection because their body cannot properly regulate the number of immune system cells (lymphocytes) and blood cells. The symptoms associated …

Feb 27, 2004 · X-linked lymphoproliferative disease (XLP) in general is characterized by an inappropriate immune response to Epstein-Barr virus (EBV) infection leading to …

People with XLP may respond to EBV infection by producing abnormally large numbers of T cells, B cells, and other lymphocytes called macrophages. This proliferation of immune cells often …

Apr 4, 2018 · Here, we describe clinical features of XLP1, how molecular and biological studies of the gene product, SAP, and the associated signaling lymphocyte activation molecule family …

Clinical characteristics: X-linked lymphoproliferative disease (XLP) in general is characterized by an inappropriate immune response to Epstein-Barr virus (EBV) infection leading to …