Mar 30, 2025 · ITGA9 (Integrin Subunit Alpha 9) is a Protein Coding gene. Diseases associated with ITGA9 include Hypotrichosis-Lymphedema-Telangiectasia Syndrome and Hennekam …

Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, …

Integrin-α9 (ITGA9) was found in guinea pig airway epithelial cells in 1991, when the polymerase chain reaction (PCR) technique showed a new α-subunit with a novel sequence compared to …

The integrin subunit ITGA9 may serve as a biomarker for the diagnosis of tumors and a potential therapeutic target for anti-tumor therapies. Keywords: ITGA9; Integrin subunits; biomarkers; …

Integrin alpha9 (ITGA9) is one of the less studied integrin subunits that facilitates accelerated cell migration and regulates diverse biological functions such as angiogenesis, …

Integrin-alpha9 overexpression underlies the niche-independent maintenance of leukemia stem cells in acute myeloid leukemia. ITGA9-AS1 up-regulates ITGA9 by targeting miR-4765 and …

shRNA-mediated ITGA9 downregulation reduced focal adhesion kinase (FAK) phosphorylation. ITGA9 expression was downregulated in cells stably transduced with two specific shRNAs …

May 27, 2022 · ITGA9 can improve cell migration and regulate various cellular biological functions, such as tumor cell proliferation, adhesion, invasion, and angiogenesis. However, its …

Mar 5, 2024 · Integrin alpha9 emerges as a key therapeutic target to reduce metastasis in rhabdomyosarcoma and neuroblastoma.

Nov 15, 2019 · Although integrin α9 (ITGA9) is known to be involved in cell adhesion and motility, its expression in cancer and its role in tumor growth and metastasis remain largely unknown. …