Protein A, B and C are isoforms encoded from the same gene through alternative splicing. A protein isoform, or " protein variant ", [1] is a member of a set of highly similar proteins that …

In genetics, gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences (CDSs) and/or …

Feb 1, 2018 · At its simplest, isoform generation provides a mechanism to specialize the properties of a gene or protein at one of three levels – DNA, messenger RNA (mRNA) or the …

Feb 29, 2024 · Here, we present IsoForma, an open-source R package for the relative quantification of PI within a single tool. Benchmarking IsoForma ’s performance against two …

W e present a first version of a human Isoform ORFeome, human isoORFeome v1.1 containing 1,423 isoforms from 506 genes, of which 917 were not previously available as ORF clones, …

Mar 30, 2016 · Alternative splicing imparts distinct functions through isoform-specific protein–protein interactions. The alternative splicing of transcripts is known to contribute to the …

Here we provide open access to 3D protein structure predictions for isoforms of 237,275 human transcripts. Individual predicted structures for CHESS 3 can be found in Isoform Search. …

We introduce a classification scheme for protein isoforms, discover novel protein isoforms, and present the first protein inference algorithm for the direct incorporation of long-read …

Aug 27, 2011 · In higher eukaryotes many genes encode protein isoforms whose properties and biological roles are often poorly characterized. Here we describe systematic approaches for …

Venn diagram showing the overlap between the number of genes that are intracellular, membrane-spanning, secreted, or with isoforms belonging to more than one of the three …