IR-780 iodide is a near-infrared lipophilic cation heptamethine fluorescent dye. It has a good fluorescent intensity and can be used as a photothermal therapy agent. It shows an optical absorption spectrum of 780 nm that makes it useful as a …

IR780 is a prototypic NIR heptamethine cyanine agent, with a high molar extinction coefficient. The maximum excitation wavelength of IR780 was 777-780 nm, and the maximum emission wavelength was 798-823 nm. IR780 can be used in cancer PTT/PDT and imaging.

IR 780 is a heptamethine cyanine fluorescent probe for in vivo imaging of tumor cells. 1 It displays excitation/emission maxima of 780/799 nm, respectively. 2 IR 780 is transported into tumor cells, an effect that can be blocked by the organic anion transporting polypeptide (OATP) inhibitor sulfobromophthalein (bromosulfalein; Item No. 21058), a...

IR 780 iodide | C36H44ClIN2 | CID 118987185 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Sep 9, 2018 · IR-780, a prototypical near-infrared (NIR) heptamethine cyanine dye, has been recently identified as the first mitochondria-targeting multifunctional NIR dye, it has excellent optical imaging and therapeutic properties and is receiving increasing attention in the field of NIR theranostic applications.

May 13, 2016 · Here, we introduce IR-780 iodide, a lipophilic heptamethine dye with a peak optical absorption of 780 nm wavelength, which can function as SDT agents for breast cancer treatment.

IR-780 iodide is a lipophilic dye with a peak emission at 780 nm and can be easily detected by the NIRF imaging system. It is reported that IR-780 can accumulate selectively in breast cancer cells and drug-resistant human lung cancer cells [6].

IR-780 iodide, a near-infrared fluorescent heptamethine dye, has been recently characterized to exhibit preferential accumulation property in the mitochondria of tumor cells. In this study, we investigated the possible mechanisms for its tumor selective …

IR-780 iodide is a near-infrared (NIR) fluorescence dye with higher and more stable fluorescence intensity than clinically applied dye indocyanine green (ICG). Meanwhile, IR-780 can be utilized in photothermal therapy with laser irradiation.

Jan 23, 2017 · While heptamethine cyanine dye IR780 has excellent tumor targeting and imaging potential, its hydrophobic property limits its clinical use. In this study, we developed nanoparticle formulations to facilitate the use of IR780 for fluorescent imaging of malignant brain tumor.