Aug 9, 2023 · Cheng et al. reveal the molecular mechanism of the widespread Gabija prokaryotic immune system, in which the synergy between GajA, an NTP-sensing DNA nickase, and GajB, a DNA-terminus-dependent (d)A/(d)GTPase, causes a cascade suicide effect to mediate defense against virulent viruses.

Nov 22, 2023 · Gabija protein A (GajA) is a DNA endonuclease that tetramerizes to form the core of the anti-phage defence complex. Two sets of Gabija protein B (GajB) dimers dock at opposite sides of the...

Mar 12, 2024 · Here, to explore how the Gabija system is activated for anti-phage defence, we report its cryo-electron microscopy structures in five states, including apo GajA, GajA in complex with DNA, GajA...

Jan 29, 2024 · Here we report the cryo-EM structure of the Gabija complex from Bacillus cereus VD045 at 3.6 Å, which provides the direct evidence of interactions between GajA and GajB. The Gabija complex is an...

Vessel O7 GAJA is a General Cargo, Registered in Antigua Barbuda. Discover the vessel's particulars, including capacity, machinery, photos and ownership. Get the details of the current Voyage of O7 GAJA including Position, Port Calls, Destination, ETA and Distance travelled - IMO 9273791, MMSI 305062000, Call sign V2HP4

May 21, 2021 · The GajA protein is revealed as a sequence-specific DNA nicking endonuclease unique in that its activity is strictly regulated by nucleotide concentration. NTP and dNTP at physiological concentrations can fully inhibit the robust DNA cleavage activity of GajA.

Vessel O7 GAJA (IMO 9273791, MMSI 305062000) is a General Cargo Ship built in 2006 and currently sailing under the flag of Antigua & Barbuda.

IMJ Institute of Research is founded on the idea that world-class research and innovation should not be confined to urban centers. By setting up our institute in a rural landscape, we aim to create an ecosystem that integrates advanced scientific exploration with grassroots development.

Giorgio Gaja is an Italian jurist. A scholar in international law, he was elected in 2012 as a judge of the International Court of Justice.

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