Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is one of the most serious extra-articular RA manifestations. RA-ILD is associated with worse physical function, lower quality of life, and increased mortality.

However, rheumatoid arthritis-associated ILD (RA-ILD) is not a single pathologic diagnosis, but rather presents with a variety of clinical, radiographic, and pathologic features that impact the natural history, response to treatment, and long-term prognosis.

Respiratory diseases particularly interstitial disease (RA-ILD) and bronchiectasis (BR) are common extra-articular manifestations of RA, with an estimated prevalence between 10 and 30% (5, 6), depending on the population analyzed and the imaging methodology used for detection.

In this review article, we shed light on the prevalence of RA-ILD and the common pulmonary manifestations of RA, while focusing on the evolving pathogenesis concepts that link them to RA's autoimmune cascade.

Jun 26, 2023 · Rheumatoid arthritis associated interstitial lung disease (RA-ILD) is one of the pulmonary manifestations of rheumatoid arthritis. There may be a greater male predilection with onset of lung disease typically occurring in the 5 th to 6 th decades of life 5.

Rheumatoid arthritis (RA) is associated with a ten-fold increased risk of interstitial lung disease (ILD). The presence of ILD in a patient with RA influences both prognosis and the choice of therapeutic intervention.

ImportanceCurrent data are lacking regarding the risk of biologic and targeted synthetic disease-modifying antirheumatic drug (b/tsDMARD) use on the development of interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA).

Interstitial lung disease (ILD) represents a frequent extra-articular manifestation of rheumatoid arthritis (RA) deeply impacting both quality of life and overall prognosis. Areas covered: A literature search was performed including PubMed, Embase, Scopus, and Web of Science.

What is rheumatoid arthritis-associated interstitial lung disease? Rheumatoid arthritis-associated interstitial lung disease, or “RA-ILD”, is a chronic lung disease in which scar tissue (“fibrosis”) and/or inflammation builds up in the walls of the air sacs of the lungs in a person with a diagnosis of rheumatoid arthritis.

4 days ago · The OR for RA-ILD development, per point increase in DAS28 over time was 1.19 (95% CI 0.34 to 4.22). Disease activity after the RA-ILD diagnosis or a matched timepoint was statistically significantly higher in patients with RA-ILD than in controls (β 0.56 (95% CI 0.18 to 0.93). There were no clear differences in DMARD use between the two groups.