The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in …

Interleukin 4 (IL-4) was first identified as a factor that was produced by T cells and could enhance the proliferative response of B cells to anti-IgM and also was capable of inducible …

IL-4 is a cytokine that functions as a potent regulator of immunity secreted primarily by mast cells, Th2 cells, eosinophils and basophils.

Mar 30, 2025 · IL4 (Interleukin 4) is a Protein Coding gene. Diseases associated with IL4 include Schistosomiasis and Allergic Disease. Among its related pathways are MIF Mediated …

Jul 1, 2003 · Interleukin-4 (IL-4) is crucial for the differentiation of naive T helper (T H) cells into the T H 2 effector cells that promote humoral (antibody) immunity and provide protection …

Mar 20, 2025 · Explore the mechanisms of IL-4 signaling, its receptor interactions, and its role in immune regulation, including effects on cytokine networks and antibody responses. Interleukin …

Nov 1, 2012 · IL-4 is a cytokine that functions as a potent regulator of immunity secreted primarily by mast cells, Th2 cells, eosinophils, and basophils.

Sep 7, 2021 · In this review, we cover critical older information but also highlight newer advances. An area of evolving interest relates to the therapeutic blockade of IL-4 signaling pathway to …

Studies of IL-4 have revealed a wealth of information on the diverse roles of this cytokine in homeostatic regulation and disease pathogenesis. Recent data suggest that instead of simple …

Oct 10, 2021 · IL-4 is known to be the quintessential regulatory cytokine, playing a role in a vast number of immune and non-immune functions. This cytokine is commonly secreted by type 2 …